BACKGROUND
    Introduction
    The 076 Dilemma
    Recommendations
    First Fruits

 

Figure 3-Life Expectancy

Figure 4-Global View

Figure 5-Prevalence in Pregnancy, S. Af.

Figure 6-Mother-to-Child

 


The Scourge of AIDS in Developing Countries.

As the AIDS pandemic stretched into its second decade, no corner of the globe seemed immune from its deadly touch. Each year added millions from all over the world to the rolls of HIV-infected people, who would number 33.4 million by the end of 1998. But the numbers were not evenly distributed. As the 1990s progressed, the toll of illness and death fell most harshly on developing countries. In 1998, for example, of 5.8 million new cases of HIV infection reported by United Nations AIDS officials, 1.2 million would come from South and Southeast Asia, and a staggering 4 million from sub-Saharan Africa.

In Africa, AIDS had reached the dimensions of a plague, sharply lowering life expectancy and even threatening to depopulate some countries. In Zimbabwe, for instance, where an estimated 26 percent of adults were infected with HIV in 1997, life expectancy had begun to decline dramatically, from 61 years in 1993 to a projected 49 years by the end of the centuryand perhaps as low as 40 ten years after that.  

Similar figures were being reported for Botswana, and other nations--including Uganda, Malawi, and parts of South Africa--were considered likely to follow suit. By the late 1990s, the 34 nations that made up the sub-Saharan region would account for 91 percent of AIDS deaths in the world.

For the millions of newly HIV-infected people in Africa, there was little hope of treatment. The expensive drug combinations available in developed countries at a cost of roughly $15,000 per person annually were far beyond the reach of most sub-Saharan nations, where per capita expenditures on health care were commonly as low as $5.00 to $10.00 a year.  

Many clinics in the region were unable to maintain adequate stocks of basic medicines and supplies, let alone the sophisticated drugs used to keep HIV at bay; few had the capacity even to provide screening for the virus, or counseling for those who tested positive.

The lack of facilities and funds made the plight of pregnant women infected with HIV especially poignant. Their numbers were growing steadily: in countries like Uganda, South Africa and Malawi, as many as 40 percent of pregnant women were estimated to be HIV-positive. Untreated, roughly one in four or five could be expected to give birth to an HIV-positive baby; those infants who escaped infection at birth faced roughly a 14 percent chance of becoming infected through breastfeeding.

Thus far, hospitals and clinics in the region had been powerless to do anything to protect the babies of HIV-positive women from infection. And, it was widely agreed, the exciting discovery of the 076 regimen did nothing to alter that harsh reality.  

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